Association Between Mannose-binding Lectin Gene Polymorphisms and Necrotizing Enterocolitis in Preterm Infants
نویسندگان
چکیده
منابع مشابه
Lactoferrin and Necrotizing Enterocolitis in Preterm Infants
Neonatal necrotizing enterocolitis (NEC) is the most important neonatal problem in nursery which is associated with high neonatal mortality and morbidity. NEC also leads to various long term complications, including short bowel syndrome, systemic infection, eye problems, nutritional deficiency and neurodevelopmental impairments. Lactoferrin (LF) is a component of breast milk and multiple action...
متن کاملAssociation between Mannose-binding Lectin Gene Polymorphisms and Susceptibility to Dengue Virus Infection: a Preliminary Report.
Mannose-binding lectin (MBL) can bind with a wide range of pathogens and can activate through lectin pathway or enhances opsonophagocytosis. MBL is encoded by the MBL2 gene and single-nucleotide polymorphisms (SNPs) in the promoter and exon have functional effects on serum levels of MBL. MBL deficiency has been shown to predispose to infectious diseases. We assess whether or not, the variant MB...
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OBJECTIVE The results of studies on the relation between Mannose-binding lectin gene (mbl2) polymorphism and HBV infection were contradictory and inconclusive. In order to shed a light on these inconsistent findings and to clarify the role of mbl2 polymorphisms in susceptibility or progression of chronic hepatitis B (CHB), a meta-analysis was performed. METHODS PubMed and Embase were searched...
متن کاملMannose-binding lectin gene polymorphisms as a susceptibility factor for chronic necrotizing pulmonary aspergillosis.
It was investigated whether a deficiency of mannose-binding lectin (MBL), which binds Aspergillus species avidly in vitro, could account for chronic necrotizing pulmonary aspergillosis (CNPA), which is seen most commonly in nonimmunocompromised patients. Blood samples were obtained from 11 patients (10 white) with CNPA and were compared with blood samples from 82 white control subjects. MBL hap...
متن کاملThe association of mannose-binding lectin 2 polymorphisms with outcome in very low birth weight infants
OBJECTIVES Studies on the influence of mannose-binding lectin (MBL) deficiency on infection susceptibility in preterm infants have yielded controversial results. We investigated the association of genotype-based MBL levels with outcome in very-low-birth weight infants (VLBWI). METHODS We genotyped 3 genetic variants of MBL2 (rs1800450, rs1800451, rs5030737) in 6878 VLBWI. MBL plasma levels we...
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ژورنال
عنوان ژورنال: Journal of Pediatric Gastroenterology & Nutrition
سال: 2012
ISSN: 0277-2116
DOI: 10.1097/mpg.0b013e31824e5f7a